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Co-enzyme B12 also interacts with the enzyme methionine synthase (5-methyltetrahydrofolate-homocysteine methyltransferase), required for the conversion of homocysteine to methionine, which is essential for folic acid metabolism and the formation of thymine, which is a component of DNA
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The response was dose-dependent, with higher doses producing slightly more fat loss, though the dose-response curve flattened at higher levels (Thompson et al., 2004)
doi:10.1503/cmaj.080727
Because your skeletal muscles are filled with mitochondria (the portion of your cell responsible for energy production in your body) and we know that B12 directly acts in these mitochondria
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