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Understanding exactly why semaglutide and tirzepatide cause or worsen GERD, and what to do about it, is the difference between managing through a temporary side effect and abandoning a program that is actually working
In fact, most patients who experience this side effect are responding well to the appetite-suppressing effects that drive weight loss
Real-world usage tells a different story, sometimes better, sometimes worse
Additionally, GLP-1 may slow stomach emptying and aid in reducing appetite, potentially contributing to weight loss
10.1016/j.mito.2013.01.008 Mitochondrion 183 VenkatakrishnanP.NakayasuE
doi:10.1371/journal.pone.0009590 38
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