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doi: 10.1177/0004867413481631 184

Duration of action can be about 6-12 hours after onset of effect

In transmethylation, the conversion of homocysteine to methionine is catalyzed by the enzyme methionine synthase, a vitamin B12-dependent zinc protein (Figure 3)

As with any treatment, one should weigh the pros and cons: PT-141 can spark arousal when needed, but may cause nausea or flushing in the process