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doi: 10.1007/s12072-021-10134-5 33 JiaoN.BakerS

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In studies using human fetal fibroblast cultures, Epithalon treatment extended cellular proliferative potential from termination at the 34th passage in control populations to beyond the 44th passage in treated cells, effectively surpassing the Hayflick limitthe maximum number of divisions normal cells can undergo before senescence

Oral administration of L-carnitine at a dose of 1 g daily increases plasma concentrations of this substance to physiological levels in patients with end-stage renal disease who are undergoing hemodialysis

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