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Chronic unpredictable stress, considered a model of depression, results in a reduction in dendritic lengths and branching of apical dendrites, the loss of functional synaptic spines, and the reduction of dendritic complexity in PFC neurons and in the hippocampal CA3 pyramidal neuronal cell layer (McEwen et al., 2012

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Bubbles indicate excessive agitation which may denature the peptide

Talking therapy and practical steps Cognitive behavioural therapy (CBT) has reasonable evidence for helping people manage AF-related anxiety