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Our previous study demonstrated that this treatment also improves metabolic markers of glutathione metabolism in these same children
When P pathway was upregulated, the accumulated -glutamyl phosphate could improve utilization of extra l-cysteine by addition of amino acid precursors for improvement of GSH synthesis
In in vivo and in vitro studies, melatonin was proven to increase the level of Nrf2 in cardiomyocytes exposed to oxidative stress
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Samples were then amplified and sequenced on a NextSeq 500 system (Illumina), where an average of 30 million reads were generated from each sample
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