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Approval Based on ESSENCE Results This approval was primarily based on positive results from Part 1 of the Phase III ESSENCE trial

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Disclosures Makam reports no conflicts of interest.

In elderly humans and animals, Epitalon treatment has been shown to increase nighttime melatonin levels toward more youthful ranges

While the focus of the study was determining the effects of semaglutides on Alcohol Use Disorder, it also found that those taking medicines like Ozempic had lower risks of developing substance use disorders not just alcohol, but a range of addictive behaviors compared to those on other diabetes medications

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