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Although TMAO is required for disease start, an animal model was first used to demonstrate the relationship between TMAO and CVD in 2011 (28)

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CKD patients most often present with atherosclerosis, thromboembolitic complications, and endothelial dysfunction, primarily due to altered endothelium-dependant relaxation factors [185]

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Unlikely, bodybuilders are more likely to use pure Human Growth Hormone