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However, more research is needed to confirm its efficacy in humans

All three components appear in the literature in overlapping tissue-repair contexts, and all three are proposed to act by mechanisms that do not obviously collide

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Of the remaining 45 articles, 6 full texts could not be retrieved and 14 were excluded as they were out of scope

The excellent tolerability is notable

Figure 5 Because CB-839 alone had a limited effect on cell proliferation and apoptosis, we examined whether the metabolic changes associated with this drug would sensitize the CLL cell lines and primary cells to the targeted therapeutics