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Horman S, Beauloye C, Vanoverschelde JL, Bertrand L (2012) AMP-activated protein kinase in the control of cardiac metabolism and remodeling

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SASP (senescence-associated secretory phenotype) results revealed that FOXO4-DRI downregulates the levels of IL-1 , IL-6 , IL-8 , and TNF- (Figure 4H)

The alternative protocol maintains a consistent dose of 2.0 mg, administered 3 times per week over the same period