When CCK binds to its receptor CCK1R, it activates vagal afferents, which send post-ingestive input to the hindbrain
Tirzepatide has a longer escalation period (20 weeks to maximum versus 16 weeks for semaglutide), which means the GI adjustment period extends over more time but may be less intense at each step
Treatment-induced mucositis: an old problem with new remedies
Some individuals are genetically programmed to store more fat in the abdominal region (android or "apple" shape), while others accumulate fat predominantly in the hips and thighs (gynoid or "pear" shape)
NAD levels decline with age, which has sparked a surge of interest in NAD IV drips, NAD injections, and oral precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN)
Original Assessment and Dosing Strategy Each patients trip starts with a complete assessment and lab testing