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Clinicians should evaluate for contraindications specific to GLP-1 receptor agonists, including: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 History of pancreatitis or gallbladder disease Severe gastroparesis or gastrointestinal disease History of suicidal ideation or behavior Pregnancy or planned pregnancy (pregnancy testing when appropriate) Diabetic retinopathy (requires monitoring in patients with diabetes) Baseline investigations should include TSH, free T4, complete metabolic panel, lipid profile, and hemoglobin A1c (if diabetic or prediabetic)

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And how can you ensure that youre taking the right steps toward your weight loss goals

Ling, L

Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats [PMID: 24385169] Laboratory literature summary: Heptapeptide semax attenuates the effects of chronic unpredictable stress in rats

Staying close to this recommendation will ensure youre eating enough for your body to function and for daily living while also eating in a way that supports healthy weight loss