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It is also important to note that this product is not intended to diagnose, treat, cure, or prevent any disease and should not be used as a substitute for medical advice

GLP-1 expression was downregulated in wild-type Lox5 cells knocked out by FNDC5, and the induced expression of lipolysis and autophagy-related genes and proteins were also inhibited, such as adipose triacylglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and hepatic lipase deficiency gene (LIPC)

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Wei X, Ma Y, Li Y, Zhang W, Zhong Y, Yu Y, et al

Fourth, the absence of corroborating human genetic or observational evidence weakens the case for continued development, particularly when coupled with marginal preclinical effects