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Phase II human trials of thymosin beta-4 (TB-500's parent molecule) have been conducted examining tissue repair rates, though detailed results remain limited in peer-reviewed literature
ROS and reactive nitrogen species can damage biomolecules in the inflammatory milieu, such as DNA, proteins and lipids, and cause malfunction to create a cycle of oxidative stress imbalance that eventually promotes tumorigenesis and progression, including cholangiocarcinoma (90)
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The benzyl alcohol in bacteriostatic water inhibits bacterial growth in the solution, extending its usable life after the sealed vial is first pierced
Notably, excess hemin exposure exacerbates the disease severity of SCD 19,20 and heme-scavenging strategies such as intravenous infusion of hemopexin are propective 21,22
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