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It makes sense mechanistically, but the hard human clinical proof is limited
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At 48 weeks, the liver fat reductions were even more pronounced, with approximately 90% of individuals receiving maximum dose levels achieving normalization of liver fat [25]
patience during the first month does not mean the medication is ineffective
Based on these outcomes, the authors stated that canagliflozin treatment is associated with possible renoprotective effects in patients with T2DM.9 The EMPA-REG OUTCOME trial10,11 included patients with T2DM and established CV disease who were at least 18 years of age
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