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Journal of Ethnopharmacology
It should be noted that the musculoskeletal evidence base remains preclinical, a 2025 scoping review by McGuire and colleagues in Current Reviews in Musculoskeletal Medicine found no adequately powered randomised controlled trials
BPC-157 meets this criterion because its clinical development (PL 14736, Diagen) stalled at phase II in 2014 and never obtained registration as a drug
BPC-157 remains investigational with limited human clinical data
A research chemical vendor in Nevada selling to California customers engages in interstate commerce, triggering federal jurisdiction
Most events were reported as mild-to-moderate and concentrated during dose escalation
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