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Vitamin B12 is a water-soluble nutrient essential for red blood cell production, DNA synthesis, and energy metabolism

Intended Use: In-vitro cell culture studies In-vivo preclinical research in approved animal models Laboratory investigation of biological mechanisms Academic and institutional research applications NOT Intended For: Human consumption or administration Therapeutic treatment or diagnosis Dietary supplementation Veterinary therapeutic applications without appropriate oversight Safety Protocols: Researchers should follow standard laboratory safety practices when handling DSIP: Use appropriate personal protective equipment (lab coat, gloves, safety glasses) Handle in well-ventilated areas or fume hood Follow institutional biosafety guidelines Dispose of waste according to local regulations for biological/chemical waste Consult material safety data sheet (MSDS) for additional safety information

doi:10.1038/s41598-022-19634-2 (PMID 36104373) U.S

The technique behind a safe B12 injection A subcutaneous B12 injection is given with clean hands, a fresh needle, the skin wiped and dried, and the needle inserted into a pinch of fat at roughly a 45 to 90 degree angle before the dose is released slowly

*Correspondence: Weina Li, [email protected] Meng Li, [email protected] These authors have contributed equally to this work This article was submitted to Drug Metabolism and Transport, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Use an interior shelf, not the door, which swings in temperature every time it opens