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Kolliphor EL solution and saline (500 L/900 mL) were used to dilute 500 L of the stock olanzapine solution and mice were injected intraperitoneally (IP) with olanzapine (5 mg/kg) or vehicle (DMSO, Kolliphor EL, saline) at the beginning of the light cycle (0900)

At that time, interest in KD for the treatment of this disease decreased and did not come to peoples attention again until the 1990s (2, 3), when its therapeutic effects were gradually found to be effective in a wide range of diseases and more therapeutic potentials of KD were proposed

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