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Clinical Efficacy In the OASIS 4 trial (the pivotal study for approval), patients taking oral Wegovy 25 mg lost an average of 16.6% of their body weight over 64 weeks compared to 2.7% with placebo

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Studies show that weight regain is common within 12 months of discontinuing GLP-1 therapy, with many individuals regaining two-thirds of what they lost (PubMed)

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