As we age, our natural collagen production slows, resulting in drooping skin, fine lines, and wrinkles
Additionally, MEGA-PRESS GSH quantification presents inherent methodological challenges: the relatively long TE (79 ms) required for J-difference editing results in T-weighted signal attenuation, and the low concentration of GSH (~ 12 mM) combined with spectral overlap necessitates careful interpretation of absolute values
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Copped et al., 2013c) suggest that it could represent an independent maternal DS risk factor with ORs ranging from 1.1 to 1.3 according to the model under investigation (Table 2)