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As shown in Figure 3A, the cumulative release of GSH was significantly enhanced in the presence of H 2 O 2 , with the 5 mM H 2 O 2 condition showing the highest release, reaching approximately 100% within 48 h

For example, in G6PD-deficient individuals, residual hepatic enzyme activity can prove insufficient in stress states where increased G6PD activity is required, as in neonates with comorbid G6PD deficiency and Gilberts syndrome, who are at increased risk for hyperbilirubinemia (96, 97)

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