The gap between these two numbers is small, which suggests that discontinuation and rescue use did not substantially dilute the treatment effect
Additional vigilance is required in individuals with a family history of, or risk factors for, pancreatitis these include high alcohol intake, gallstones, and high triglycerides[511]
Cocaine binds to the norepinephrine transporter (NET) and other closely related monoamine transporters (DAT & SERT) at a common core area known as the central substrate-binding site, also referred to as the S1 pocket (Acharya Dahal et al., 2014
None of that is alarming at sensible doses, and the heart rate change reported in trials was minor, but it is the same receptor doing both jobs
GLP-1 medications are best if taken long-term, but shortages, price, and side effects like GI discomfort are potential barriers for some
Several patient characteristics may increase susceptibility to gastroparesis symptoms during GLP-1 therapy