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Consult with your doctor, make sure your A1C is at a good level, think through your design for as long as it takes, and then go under the needle with confidence that you are doing the right thing

With regular use, you may notice a significant reduction in the visibility of dark spots and blemishes, leading to a smoother and more uniform complexion

Hydration deserves a plan because fasting can mask thirst

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Data availability Source data underlying graphs presented in the main figures can be found in Supplementary Data 1 and are available from the corresponding author on reasonable request

These side effects, while manageable in many cases, require careful consideration, especially in patients with pre-existing gastroesophageal issues