While blood pressure lowering is not the sole driver of these outcomes, it likely contributes to the overall cardiovascular benefit
The most frequently reported AEs were gastrointestinal (GI) in nature, and they occurred more often with semaglutide than placebo in both males and females
Annie DePasquale, MD, a board-certified family medicine physician and Founder of Collaborating Docs, adds that while Zepbound starts working almost immediately to suppress appetite, with blood sugar control within days to weeks of starting treatment, significant weight loss develops gradually. Zepbound works by slowing gastric emptying (how quickly food leaves your stomach) and improving insulin sensitivity
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Medications such as Topamax (topiramate) and Semaglutide have gained attention for their potential to aid weight loss when used correctly
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