As discussed in Section 2.3, this pathway is influenced by oxidative stress and plays a protective role in the acute phase by promoting cardiomyocyte survival and upregulating anti-apoptotic and antioxidant proteins (Liu P
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Annu Rev Pharmacol Toxicol 45:5188 Hirrlinger J, Dringen R (2005) Multidrug resistance protein 1-mediated export of glutathione and glutathione disulfide from brain astrocytes