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However, the current activity of LaccID is still much lower than that of APEX2 or TurboID, requiring 12 h of labeling to give detectable signal, in contrast to APEX2 or TurboID, which need only 110 min
Signs your current concentration is too low If you are drawing more than 80 units per dose, your concentration may be too low
For background on the copper tripeptide itself, Wikipedias GHK-Cu overview provides foundational context
Animal model studies demonstrate a biphasic response curve where low micromolar concentrations (110 M) produce maximal NF-B inhibition, while concentrations above 50 M show diminishing returns and, in some tissue types, paradoxical pro-inflammatory signaling
Alscher RG (1989) Biosynthesis and antioxidant function of glutathione in plants