The single published human case series and unpublished clinical trial data provide preliminary safety reassurance but insufficient evidence for clinical efficacy claims
Premature neonates are particularly at risk because their kidneys are immature, and they require large amounts of calcium and phosphate solutions, which contain aluminum
81 A study in anxious dogs showed treatment with the probiotic yeast Saccharomyces boulardii, at 1 billion CFUs per kg of dog food daily for 35 days, decreased levels of cortisol, suggesting stress reduction
Thus the best-known "function" of B 12 (that which is involved with DNA synthesis, cell division, and anemia) is a facultative function that is mediated by B 12 -conservation of an active form of folate which is needed for efficient DNA production
However, the independent confirmation by Sun et al
How B12 Supports Nerve Function and Red Blood Cell Formation Vitamin B12 is vital for making red blood cells and keeping nerves healthy