For patients with obesity, type 2 diabetes, or significant metabolic syndrome, GLP-1 medications have strong evidence and meaningful clinical outcomes
Unlike metformin, which has a well-established association with B12 deficiency, tirzepatide has not demonstrated a direct mechanism affecting B12 absorption
For IM, stretch it taut
beta-3 adrenergic and adipocyte signaling Standard dose / 250 to 500 mcg subcutaneous once daily (503A compounding) Key trial / Heffernan et al
Interest in NAD+ injection protocols has grown as clinicians develop wellness and longevity programs for their patients
Peptide therapies are commonly discussed for wellness goals such as recovery support, healthy aging, body composition, performance optimization, sleep support, and overall vitality