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Another study published in the Journal of Clinical Endocrinology & Metabolism found that a GLP-1 agonist was effective in reducing body weight and BMI in obese women with PCOS who were also being treated with metformin, a medication commonly used to treat insulin resistance
As such, stigmas persistespecially in the running community where good ol grit is valued over a perceived quick fix to nail performance gains
10.1016/j.tem.2012.11.008
These medications are not recommended for people with a personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), or those who are pregnant or breastfeeding
An RCT in 50 infertile men found that NAC (600 mg/day for 3 months) significantly improved sperm concentration, motility, and morphology and reduced oxidative stress markers (Ciftci et al., Urology, 2009) [69]
Why the caveats: Most human data is observational, not randomized controlled trials designed to prove prevents dementia. So far, we cannot definitively say GLP-1 RAs prevent Alzheimers
