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PREVENT: a randomized, placebo-controlled crossover trial of avexitide for treatment of postbariatric hypoglycemia
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In laboratory studies, GLP-1 RAs decrease de novo lipogenesis by down-regulating SREBP-1c and up-regulating AMPK, enhance -oxidation through PPAR- activation, and reduce oxidative stress through cAMP-PKA-mediated pathways [21, 24]
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Low blood glucose (hypoglycemia)
Interestingly, different doses of Vit K1 significantly reduced hepatic necrosis and the APAP-triggered elevation in blood activities of ALT and AST, while restoring serum albumin levels to a level near the control line
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