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168 SATURATED FAT FAVORABLY ALTERS THE GUT MICROBIOTA AND IMPROVES SURVIVAL IN PATIENTS WITH SEVERE ALCOHOLIC HEPATITIS: A RANDOMIZED CONTROLLED TRIAL Harshita Tripathi 1 , Jaya Benjamin 2 , Shvetank Sharma 1 , Rakhi Maiwall 2 , Vinod Arora 1 , Chhagan Bihari 3 , Guresh Kumar 1 , Yogendra Kumar Joshi 2 and Shiv Kumar Sarin 3 , (1)Institute of Liver and Biliary Sciences, New Delhi, India, (2)Institute of Liver and Biliary Sciences, New Delhi, (3)Institute of Liver and Biliary Sciences Background: Severe alcoholic hepatitis (SAH) is associated with malnutrition, dysbiosis and inflammatory cytokines augmenting liver injury resulting in high mortality

Rats received an IP injection immediately prior to dark cycle onset of either vehicle (1 ml/kg), sCT (3 g/kg), liraglutide (50 g/kg) or a combination of both sCT and liraglutide 10,15,33,65,71,72,73,74

Its going to prevent them from having sleep apnea

Semaglutide-treated rats show downregulation of many type IV and type VI collagens and laminin genes that compose the basement membrane, as well as the type I, type III, and type V collagens and fibrillins that compose the interstitial matrix ( Figure 4B )

Central nervous system effects on appetite appear to complement GLP-1 signaling through distinct neurological pathways

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