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Due to massive and persistent cultural and patient resistance and restrictive regulations, opioid-based OUD treatments like methadone and buprenorphine are used by a small fraction of people who could benefit from them

Creating a calm environment for your first dose and keeping track of how you feel afterward can also be helpful

For most patients, the first dose is administered in the week preceding further therapy, with follow-ups every few weeks to help alleviate symptoms and support better health outcomes

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