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Oncotarget 7 , 5050750521 (2016)

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Brazil's Supreme Federal Court had previously established a relevant precedent in ADI 5529, it struck down automatic patent term extensions for pharmaceutical patents and the STJ applied consistent logic in denying the compensatory extension Novo Nordisk had sought

Studies have demonstrated that GRR alleviates DBL-induced liver injury by modulating FXR/Nrf2BA-related proteins and increasing the relative abundance of Muribaculaceae, thereby reducing hepatic BA accumulation and mitigating liver inflammation and oxidative stress via the gut-liver axis [165]