The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications
Insulin signaling can promote cell proliferation and survival, while excess circulating glucose can fuel rapid cell growth and contribute to cell death resistance, promoting cancer development and progression
Keratin Matrix Fortification for Brittle Nails Delivers a concentrated elemental Zinc and Vitamin E matrix directly to the nail bed to repair lipid membranes
GLP-1 RAs Hold Promising Potential for Reduction of Cardiometabolic Risk Factors additional benefits : Brain: Appetite suppression, nerve protection, and decreased neuroinflammation Heart: Decreased blood pressure (systolic and diastolic), reduced total cholesterol levels, lowered endothelial dysfunction, and increased heart rate Liver: Decreased glucose production Pancreas: Increased insulin secretion, decreased glucagon secretion, B islet cell proliferation GI Tract: Decreased gastric emptying Because these drugs cause weight loss, it is not clear whether the GLP-1 RAs or the weight loss reduces cardiometabolic risks
We believe that the mechanistic pathways uncovered here have potential for impact in the clinical context of IRI, for which no approved therapies currently exist
Don't Forget Lifestyle Factors Nutrition is important, but other habits also matter