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As stated in the SmPC, a maintenance dose of 1.7 mg may be considered if patients cannot tolerate the 2.4 mg dose

"The curation of leading next generation therapies, advancements in early diagnostics, and even personalization based on whole-genome sequencing is of top focus for potential partnerships," executives said in a press release

There is a deeper irony embedded in this practice: If buyers believed these products were safe, properly characterized and manufactured to the standards expected of pharmaceutical-grade products, they would not need to commission independent purity tests

R For COMT Met/Met patients, methylation support (adequate B vitamins , magnesium , and SAM-e if tolerated) helps compensate for the reduced enzyme activity

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Studies show it can enhance the absorption of beta-carotene, curcumin, selenium, vitamin B6, and coenzyme Q10, among other nutrients