Creatine also plays a role in brain energy metabolism, and some research suggests it may support cognitive function
Your heart rate increases, blood vessels constrict, and you may hold your breath or breathe shallowly
If youre taking an antidepressant, dont stop taking it unless youre instructed to by your provider
For constipation, increasing fibre, fluids, and physical activity may help
Those with pre-existing gastrointestinal conditions, such as irritable bowel syndrome or inflammatory bowel disease, should receive individualised guidance from a registered dietitian, as standard fibre recommendations may require modification (for example, emphasising soluble fibre or considering a dietitian-supervised low FODMAP approach)
Phase 2 data published in the New England Journal of Medicine (2023) demonstrated substantial weight loss in adults with obesity, but the medicine is not yet approved for clinical use in the UK