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Prescription options for refractory cases include lubiprostone (Amitiza), linaclotide (Linzess), plecanatide (Trulance), and prucalopride (Motegrity)
Paired biopsies before and 1 year after surgery were available in 146/232
A GHSR inverse agonist named PF-5190457 is under clinical investigation to treat alcohol use disorder 10,11
1 Two reviewers, independently and in duplicate, screened the titles and abstracts of the identified studies, excluding irrelevant studies
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Most plans also require documentation of a structured lifestyle intervention attempt of at least 3 to 6 months
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