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SGLT2 inhibitors contribute to switching energy metabolism and reinstate mTOR activity in cardiovascular system, and by restoring mTOR cycle may interfere with a cognitive impairment (Packer, 2020

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To date, two incretins, glucagon like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), have been identified

Through SA--gal staining, we found that FOXO4-DRI also reduced the number of positive cells in the aorta of D-galactose induced aged mice (Figure 2C)