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When To Call Your Clinician Versus When to Head to the Emergency Department Call your clinician promptly if symptoms last more than a few days, get worse, or stop you from doing daily tasks like working or keeping fluids down

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The upregulation of IGFBP4 (encodes for a protein that binds insulin-like growth factors I and II 26 ), was shown to function as a potent tumor suppressor in hepatocellular carcinoma and delay tumor formation in prostate cancer cells 41,42

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