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Genetic Variants in Phosphatidylethanolamine N-Methyltransferase (PEMT) and Methylenetetrahydrofolate Dehydrogenase (MTHFD1) Influence Biomarkers of Choline Metabolism When Folate Intake Is Restricted. Journal of the American Dietetic Association, vol
Mater Adv (2022) 3(18):695067
Research published in the context of the SURPASS trial program demonstrated that tirzepatide produced dose-dependent HbA1c reductions of 1.24 to 2.58 percent across the studied dose range, and body weight reductions of 5.4 to 11.7 kilograms in patients with type 2 diabetes
This is about the same as tirzepatide's effect, but it's done through different receptor pathways
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