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In addition, the enzyme did not tolerate photoreduction in the presence of EDTA ( Results SmTGR C159S reductive half-reaction Published X-ray crystal structures of SmTGR reveal what appears to be a chain of three cysteine pairs which could act as electron carriers to move electrons derived from NADPH to specific parts of the enzyme to reduce oxidant substrates (Figure 1

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

There is limited clinical evidence available

They accumulate with age and secrete inflammatory factors (SASP) that can damage surrounding healthy tissue, contributing to age-related decline and disease