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Trials 23 , 170 (2022)
This rapid skeletal muscle tissue damage and intramuscular infiltration of immune cells contribute to PEM-related symptoms
In conditions characterized by chronic immune dysregulation, such as autoimmunity in Long COVID, the failure of this delicate S-glutathionylation process contributes to sustained tissue damage and cellular miscommunication
Specifically, berberine can cause: Nausea Diarrhea Stomach cramps Bloating Headache Constipation (particularly when you stop taking it) Rashes (though this is relatively rare) The more berberine you take, the more likely you are to experience these side effects
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