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Image Credit: New Africa / Shutterstock Background Obese or overweight individuals are generally at a higher risk of cardiovascular and metabolic diseases and have higher morbidity and mortality rates in comparison to individuals within the normal weight range

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Apart from the well-documented GPx-like catalytic activity, ebselen is also reported for directly scavenging the biologically relevant ROS (like peroxyl and singlet oxygen) and reactive nitrogen species (peroxynitrite) with rate constants comparable to standard antioxidants

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Encapsulation of exenatide in poly-(D, L-lactide-co-glycolide) microspheres produced an investigational long-acting once-weekly formulation for type 2 diabetes

These two modalities can be linked through the concept of a provocative test. Because refractory migraine is a heterogeneous disorder, patients with centrally mediated or multifactorial pain syndromes (eg, related to prior craniotomies) are unlikely to benefit from peripheral MMA intervention