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In conclusion, MASLD pathogenesis involves complex interactions among multiple metabolic pathways, including dysregulated lipid metabolism, insulin resistance, inflammation, and oxidative stress

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The de novo biosynthesis of arginine is carried out through the urea cycle, a process of ammonia detoxification by conversion to non-toxic urea

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The expression of iNOS is induced by exposure to allergens, pro-inflammatory cytokines (IL-1, IFN-, TNF-), bacterial lipopolysaccharide, and pro-oxidants (92)