Pickart 2015 BioMed Res Int sequenced by Affymetrix chip the effects of 10 nM GHK-Cu on human fibroblasts after 24h: 4192 significantly modulated genes, including activation of DNA repair programmes (NBN, BRCA1), regeneration (collagens, elastin, integrins), antioxidant defence (glutathione peroxidase, SOD, peroxiredoxins) and anti-inflammatory modulation (reduction of TNF-alpha, IL-6, IL-8)
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The organic solvent was evaporated under reduced pressure at 30 C using a rotary evaporator (IKA RV 10, Staufen, Germany) operating at 180 rpm and 380 mbar, producing a viscous organogel
Within both groups, mice were subdivided to receive subcutaneous semaglutide or saline for 15 days (Supplementary Fig