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The significance of this paper is not only to compare the three routes of administration but also to evaluate them and determine which route is the best to administrate the drug

The hippocampal atrophy observed in chronic depression corresponds to reduced BDNF signaling and impaired neurogenesis

Presented for research literature review only Maganhin CC et al

Depletion of glutathione peroxidase 4 (GPX4), an enzyme that lowers lipid hydroperoxides and inhibits lipid peroxidation, is the main cause of ferroptosis in macrophages (60)

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