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Jing, J
Increases in resting heart rate are a recognised class effect of incretin-based therapies and have been reported with GLP-1 receptor agonists more broadly, as reflected in the Summary of Product Characteristics (SmPC) for licensed agents such as semaglutide (Wegovy) and liraglutide (Saxenda)
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It forms a crystalline matrix that physically separates peptide molecules, preventing the ice crystal formation that can mechanically damage delicate peptide structures
The blend seems to support subchondral vascular ingress, which is sometimes needed for repair or to stabilize microvascular channels
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