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Baseline cohort definitions include demographic characteristics (e.g., age, sex, race/ethnicity, diabetes duration, smoking rate), relevant biomarkers (e.g., HbA1c, systolic and diastolic blood pressure, total cholesterol, low- and high-density lipoprotein, triglycerides, BMI, heart rate, white blood cell count, and estimated glomerular filtration rate), and history of micro- and macrovascular complications (e.g., eye disease, diseases of the lower extremities, kidney disease, heart disease, heart attack, heart failure, and stroke)
The report shows that the number of 12- to 25-year-olds using any GLP-1 drug including older medications first approved to treat diabetes in 2005 and for weight loss in 2014 climbed from about 8,700 a month in 2020 to more than 60,000 a month in 2023, a nearly 600% increase
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In the specific context of sleep promotion and nervous system protection, the spotlight turns to endogenous peptides
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