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We developed a sensitive, high-throughput, scalable system for profiling the cleavage activity of natural and evolved BoNT proteases on thousands of substrates simultaneously by adapting the genetic circuitry of PACE into a pooled activity-enrichment assay

Recent advances in the modulation of pain by the metabotropic glutamate receptors

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Awasthi YC, Sharma R, Cheng JZ et al (2003) Role of 4-hydroxynonenal in stress-mediated apoptosis signaling

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IGF-1R protein is overexpressed in more than 40% of breast cancer (BC