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2034 Evaluating the impact of missing data on scale reliability: A simulation study of a 10-Item HRQOL COA with varying item properties Adrian Jewett 1 1 Lumanity, Los Angeles, California, USA Journal of Patient-Reported Outcomes 2026 , 10(Suppl 1) :2034 Aims Many COAs allow up to 50% of items to be missing, assuming that all items are interchangeable, which is rarely the case
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The US FDA however, considers hydroquinone to be safe
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